For when anxiety follows you everywhere

Total Stress Support

Name: Total Stress Support
Brand: The Upside
SKU: SSYCAP30
Price: 1499.0 INR
Availability: InStock

Click ingredients for clinical evidence & research

TOTAL STRESS SUPPORT: SYNERGISTIC DUAL PHASE EIGHT INGREDIENT SYSTEM

Breaks the Day & Night Stress-Sleep-Stress Cycle
Suppers cortisol elevation, maintains day-to-day calm
Builds long-term stress resilience

When to take: Clear Days anytime in the day | Quiet Nights 30-60 minutes before day

Stable mood
Stable emotions
Inner calm

₹1,499.00

₹24.98 each

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How we got here

Sleep isn't a nighttime problem

Most people treat sleep as something that happens at night. But the quality of your sleep is determined long before you get into bed, by how your cortisol behaved during the day, how much your nervous system was asked to carry, and whether your body had what it needed to wind down properly.

Stress and sleep are the same system

Your stress system and your sleep system are not separate. They run on the same chemistry, the same hormonal pathways, the same neurotransmitters. When the stress system is dysregulated during the day, the sleep system pays for it at night. Treating one without the other only gets you so far.

We support the full cycle

Total Stress System covers the complete architecture. From the cortisol regulation and calm focus of the day, through the wind-down and neurotransmitter production of the evening, into the sleep quality and overnight repair that determines how tomorrow begins.

The Chewable Form

Bite. Chew. Swallow.

Built to carry grams of actives, not milligrams. These are doses a gummy can't hold
Starts absorbing in your mouth, before it reaches your stomach
No water, no residue, no fuss
Tastes good enough to make it a ritual, not a chore

Multi-Active Synergistic Approach

Eight ingredients working across the full stress-sleep cycle - cortisol regulation, neurotransmitter production, nervous system support, temperature regulation and overnight repair.

The when

Twice daily for full cycle support. One in the morning to support the stress system through the day, one in the evening to support the wind-down into sleep.

Total Stress Support

₹1,499.00

₹24.98 each

Patent pending

No melatonin, no dependency

Formulated by experts across pharmacology, dietetics, nutrition and toxicology

Multi-pathway synergistic formulation

SCIENCE, EXPLAINED.

FROM BASICS TO BIOLOGY TO RESEARCH

THE BASICS

You get through the day without running on empty by noon.

The transition from day to night happens without effort.

Sleep arrives without the usual delay and does what sleep is supposed to do.

The morning reflects the night so you wake up as someone who actually rested.

THE BIOLOGY

It regulates the stress response through the day.

Ashwagandha KSM-66 works on the HPA axis, calibrating the cortisol response so the body reacts proportionately to what's actually happening rather than running in a state of low-level activation all day. A well-regulated stress system during the day means a nervous system that can actually stand down at night.

It supports mood and focus without forcing either.

Saffron supports serotonin availability, Sustained Release L-Theanine promotes calm alert focus through alpha wave activity, and Vitamin B6 maintains the cofactor supply that neurotransmitter production depends on. Together they support the quality of the day - steady, clear and functional rather than edgy, depleted or flat.

It restores what the day takes.

Magnesium is depleted by stress. As the day runs down the body's reserves, the nervous system's ability to regulate itself reduces. Total Stress Support restores that availability so the system doesn't compound its own depletion into the evening.

It converts the day into the conditions for sleep.

L-Tryptophan feeds the serotonin-to-melatonin cascade, helping the body run its own sleep-signalling process. L-Ornithine clears ammonia, the metabolic residue of a day under pressure, reducing the fatigue and restlessness that uncleared stress byproducts create. Quercetin reduces neurological noise through GABA activity, quieting the alert system.

It carries into the next day.

When the stress system is well supported during the day and the sleep system completes properly at night, the brain clears better, cortisol starts the next day at a healthier baseline and the cycle becomes self-reinforcing rather than self-depleting.

THE RESEARCH

Ashwagandha and HPA axis regulation.

Ashwagandha KSM-66 modulates the hypothalamic-pituitary-adrenal axis, reducing serum cortisol and perceived stress scores in randomised controlled trials. By acting at the source of the stress hormone cascade rather than masking downstream symptoms, it supports sustained regulation across the full day.

Saffron and serotonin reuptake.

Crocin and safranal, the active compounds in saffron, inhibit the reuptake of serotonin, dopamine and norepinephrine, increasing their availability across the day. Serotonin is also the direct precursor to melatonin, making daytime serotonin support directly relevant to sleep onset at night.

Sustained Release L-Theanine and alpha wave induction.

Sustained-release L-Theanine maintains alpha wave frequency - the brain state of relaxed alertness - across several hours rather than peaking and declining. This supports focus and calm through the working day without the edge that stimulants create or the crash that follows them.

L-Tryptophan and the serotonin-melatonin cascade.

L-Tryptophan crosses the blood-brain barrier and converts to 5-HTP, then serotonin, then melatonin via the pineal gland. Supplementing at therapeutic levels increases substrate availability across the entire cascade, supporting both daytime mood regulation and the natural hormonal pathway that initiates sleep.

L-Ornithine and metabolic clearance.

L-Ornithine is a key intermediate in the urea cycle. Under physical or psychological stress, ammonia accumulates as a metabolic byproduct. Ornithine facilitates its conversion to urea for excretion, reducing fatigue markers and improving subjective sleep quality and next-day alertness.

Quercetin and GABAergic activity.

Quercetin modulates GABA-A receptors, increasing inhibitory tone in the central nervous system without disrupting sleep architecture. It reduces the low-level neurological noise that keeps the nervous system in a mild alert state, supporting the transition into sleep without suppression.

the evidence

L-Theanine 200mg

Promotes alpha brain wave activity - the same relaxed-but-alert state you're in just before sleep, or right after a good meditation.

🔗

Hidese, Shinsuke, et al.

"Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial."

Nutrients, vol. 11, no. 10, 2019, article 2362, https://doi.org/10.3390/nu11102362.

Single Dose 4 Weeks

Reduced cortisol by

40%

within 1 hour

Increased dopamine and serotonin within

30mins

Increases alpha brain waves

56-70%

within 3 hrs

Improves overall sleep quality by

14.2%

over 4 weeks

Helps you fall asleep

26%

faster

Improves daytime functioning by

31%

Reduces anxiety by

6.6%

over 4 weeks

Saffron 30mg
(Crocus Sativus Extract)

Promotes alpha brain wave activity - the same relaxed-but-alert state you're in just before sleep, or right after a good meditation.

🔗

Sadat Rafiei, Seyyed Kiarash, et al.

"Saffron and Sleep Quality: A Systematic Review of Randomized Controlled Trials."

Nutrition and Metabolic Insights, vol. 16, 2023, article 11786388231160317.

After 4 Weeks

Improves overall sleep quality by

24.6%

Improves mood upon awakening by

+14.42%

Improves sleep satisfaction scores by

+16.81%

Magnesium & Vit B6

A cofactor in over 300 enzymatic reactions - including the ones that regulate stress response, muscle relaxation, and sleep architecture.

Supports the

HPA axis

and helps reduce cortisol response

Helps break the stress-

magnesium depletion cycle -

chronic stress depletes magnesium, low magnesium worsens stress

Enhances deep,

restful sleep

L Ornithine 400mg

Clears ammonia - the waste product your body builds up during the day - so your brain can finally power down at night.

🔗

Miyake, Mika, et al.

"Randomised Controlled Trial of the Effects of L-Ornithine on Stress Markers and Sleep Quality in Healthy Workers."

Nutrition Journal, vol. 13, 2014, article 53.

After 4 Weeks

26%

reduction in the cortisol/DHEA-S stress ratio

47%

reduction in insomnia symptoms from baseline

100%

improvement in ability to fall asleep & stay asleep

14%

improvement in sleep duration from baseline

L - Tryptophan 1g

The raw material your brain converts into serotonin and then melatonin - the two molecules most directly responsible for mood stability and sleep onset.

🔗

Hartmann, Ernest, and Cheryl L. Spinweber.

"Sleep Induced by L-Tryptophan: Effect of Dosages within the Normal Dietary Intake."

The Journal of Nervous and Mental Disease, vol. 167, no. 8, 1979, pp. 497-499.

49%

reduction in time spent awake after Sleep onset

Reduces sleep latency (falling asleep faster) by

30%

Quercetin 100mg

A powerful antioxidant and anti-inflammatory that also acts as a natural antihistamine - reducing the systemic low-grade inflammation that can disrupt sleep quality.

Reduces

inflammatory and allergic immune responses.

L-Theanine▾

L-Theanine 200mg

Promotes alpha brain wave activity - the same relaxed-but-alert state you're in just before sleep, or right after a good meditation.

🔗

Hidese, Shinsuke, et al.

"Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial."

Nutrients, vol. 11, no. 10, 2019, article 2362.

Single Dose

Reduced cortisol by

40%

within 1 hour

Increased dopamine and serotonin within

30mins

Increases alpha brain waves

56-70%

within 3 hrs

4 Weeks

Improves overall sleep quality by

14.2%

over 4 weeks

Helps you fall asleep

26%

faster

Improves daytime functioning by

31%

Reduces anxiety by

6.6%

over 4 weeks

Saffron Extract▾

Saffron Extract 30mg
(Crocus Sativus Extract)

Promotes alpha brain wave activity - the same relaxed-but-alert state you're in just before sleep, or right after a good meditation.

🔗

Sadat Rafiei, Seyyed Kiarash, et al.

"Saffron and Sleep Quality: A Systematic Review of Randomized Controlled Trials."

Nutrition and Metabolic Insights, vol. 16, 2023, article 11786388231160317.

After 4 Weeks

Improves overall sleep quality by

24.6%

Improves mood upon awakening by

+14.42%

Improves sleep satisfaction scores by

+16.81%

Magnesium▾

Magnesium & Vit B6

A cofactor in over 300 enzymatic reactions - including the ones that regulate stress response, muscle relaxation, and sleep architecture.

Supports the

HPA axis

and helps reduce cortisol response

Helps break the stress-

magnesium depletion cycle -

chronic stress depletes magnesium, low magnesium worsens stress

Enhances deep,

restful sleep

L Ornithine▾

L Ornithine 400mg

Clears ammonia - the waste product your body builds up during the day - so your brain can finally power down at night.

🔗

Miyake, Mika, et al.

"Randomised Controlled Trial of the Effects of L-Ornithine on Stress Markers and Sleep Quality in Healthy Workers."

Nutrition Journal, vol. 13, 2014, article 53.

After 4 Weeks

26%

reduction in the cortisol/DHEA-S stress ratio

47%

reduction in insomnia symptoms from baseline

100%

improvement in ability to fall asleep & stay asleep

14%

improvement in sleep duration from baseline

L - Tryptophan▾

L - Tryptophan 1g

The raw material your brain converts into serotonin and then melatonin - the two molecules most directly responsible for mood stability and sleep onset.

🔗

Hartmann, Ernest, and Cheryl L. Spinweber.

"Sleep Induced by L-Tryptophan: Effect of Dosages within the Normal Dietary Intake."

The Journal of Nervous and Mental Disease, vol. 167, no. 8, 1979, pp. 497-499.

49%

reduction in time spent awake after Sleep onset

Reduces sleep latency (falling asleep faster) by

30%

Quercetin▾

Quercetin 100mg

A powerful antioxidant and anti-inflammatory that also acts as a natural antihistamine - reducing the systemic low-grade inflammation that can disrupt sleep quality.

Improved

Reduces inflammatory and allergic immune responses.

UPSIDE’S INGREDIENT LIBRARY

Vitamin B6

Vitamin B6

(Pyridoxine HCl)

A water-soluble vitamin. If you want it from your plate, eat chickpeas, salmon, chicken, bananas and potatoes.

FOUND IN

Clear Days · Total Stress Support · Steady State

EXPLORE INGREDIENTS

Questions worth asking

If my body already has a stress response, why does it need help? 

It usually manages, until the load exceeds what the system can keep up with. Stress depletes magnesium, runs down neurotransmitter precursors and keeps cortisol elevated in ways that compound over time. Total Stress Support doesn't replace your stress response. It replenishes what that response burns through, so the system keeps working the way it's supposed to across the full day and into the night.

Will Clear Days make me drowsy during the day? 

No. Sustained Release L-Theanine is specifically associated with calm alertness, not sedation. The AM ingredients are chosen for daytime use. You shouldn't feel quieted or foggy - the intention is that you feel more steady, not less present.

Will Quiet Nights knock me out? 

No. The PM ingredients support your body's natural wind-down process - they don't sedate or force sleep. The shift is felt as ease rather than heaviness. You stop mentally replaying the day, the tension releases, and sleep arrives without the usual resistance. There's no grogginess the morning after.

Do I need to take both, or can I just take one? 

One is better than none. The AM dose supports the stress system through the day. The PM dose supports the wind-down and sleep. Together they cover the full cycle, which is where the formula is most effective. That said, if your main concern is daytime stress, AM alone is a valid starting point. If sleep is the primary issue, PM alone addresses the evening and night. Most people find that taking both is where the meaningful difference shows up, because the two ends of the cycle are connected.

When will I start noticing a difference? 

The L-Theanine effect from the AM dose is often felt within the first day, a quieter edge, more even focus. The PM ingredients support the wind-down from the first evening, though the shift is subtle rather than dramatic. The adaptogenic ingredients, particularly Ashwagandha, build over two to four weeks of consistent use. The most meaningful shift is observing that better days lead to better nights that lead to better days - and that comes from daily use over time.

What if my stress is situational - a hard period at work or a difficult time personally? 

Situational stress is still physiological stress - cortisol rises, magnesium depletes, neurotransmitter production gets stretched. Total Stress Support works on the biology of that response regardless of what's causing it. It won't resolve the situation, but it means your system isn't also working against you while you navigate it.

What if I forget to take AM in the morning. Can I take it later in the day? 

Yes. Taking it later is better than skipping it entirely. The morning is the optimal window. The adaptogens and mood-supporting ingredients work best when they're in your system before the day's demands build up. But if you miss the morning, take it when you remember and continue as normal.

Can I take Clear Days and Quiet Nights on the same day? 

Yes, that's the intended approach for full cycle support. Clear Days in the morning, Quiet Nights in the evening. The ingredients don't overlap in a way that creates any issue, and taking both is what gives the formula its full effect across the stress-sleep cycle.

What if I take PM and still can't sleep? 

The PM ingredients support the conditions for sleep, they don't force it. If sleep doesn't come, the cause may be environmental (light, noise, room temperature), habitual (screens, late eating) or something that needs more consistent support over time. It's also worth considering whether 3AM Rescue or Sleep Repair would help address what's happening further into the night.

Total Stress Support

Click ingredients for clinical evidence & research

FROM BASICS TO BIOLOGY TO RESEARCH

It regulates the stress response through the day.

It supports mood and focus without forcing either.

It restores what the day takes.

It converts the day into the conditions for sleep.

It carries into the next day.

Ashwagandha and HPA axis regulation.

Saffron and serotonin reuptake.

Sustained Release L-Theanine and alpha wave induction.

L-Tryptophan and the serotonin-melatonin cascade.

L-Ornithine and metabolic clearance.

Quercetin and GABAergic activity.

the evidence

L-Theanine 200mg

Saffron 30mg(Crocus Sativus Extract)

Magnesium & Vit B6

L Ornithine 400mg

L - Tryptophan 1g

Quercetin 100mg

L-Theanine 200mg

Saffron Extract 30mg(Crocus Sativus Extract)

Magnesium & Vit B6

L Ornithine 400mg

L - Tryptophan 1g

Quercetin 100mg

UPSIDE’S INGREDIENT LIBRARY

L-Theanine

FOUND IN

FOUND IN

Saffron Extract

FOUND IN

Magnesium

FOUND IN

(Pyridoxine HCl)

FOUND IN

L-Theanine

FOUND IN

FOUND IN

Saffron Extract

FOUND IN

Magnesium

FOUND IN

(Pyridoxine HCl)

FOUND IN

Questions worth asking

For when anxiety follows you everywhere

Saffron 30mg
(Crocus Sativus Extract)

Saffron Extract 30mg
(Crocus Sativus Extract)